DNA Amplification

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Polymerase chain reaction (PCR) is a technique widely used in molecular diagnostics to amplify sequencing of DNA. PCR is enabled by a machine called a thermocycler, which rapidly heats and cools the DNA sample to a defined series of temperature steps.

Modern thermocyclers used for real-time and digital PCR testing utilize Peltier technology to precisely manage the set point temperatures and ramp rates. This is a harsh environment for standard thermoelectric coolers due to the mechanical stresses that occur during the heating and cooling stage.


PowerCycling PCX Thermoelectric Coolers

Laird Thermal Systems’ PowerCycling PCX Series thermoelectric coolers are designed for high reliability applications such as PCR thermal cycling, which require extended mean time between failure (MTBF). Assembled with next generation thermoelectric materials, the PCX series offer faster ramp rates compared to standard thermoelectric coolers.

Find PCX Series or read more about thermoelectric coolers for PCR in our application note Next Generation Thermoelectrics Designed for Real-Time PCR